Identifying Molecular Regulators of Neuronal Functions Affected in the Movement Disorder Dystonia PRINCIPAL INVESTIGATOR:
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چکیده
Background: An in-frame deletion leading to the loss of a single glutamic acid residue in the protein torsinA (DE-torsinA) results in an inherited movement disorder, DYT1 dystonia. This autosomal dominant disease affects the function of the brain without causing neurodegeneration, by a mechanism that remains
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